Majors offered at University of Puerto Rico at Cayey are classified by the U.S. Department of Education under the following instructional programs:

	Associates	Bachelors	Certificate	Masters	Doctoral
Accounting
Administrative Assistant and Secretarial Science, General
Biological and Biomedical Sciences
Biological and Biomedical Sciences, Other
Biology/Biological Sciences, General
Business Administration and Management, General
Business, Management, Marketing, and Related Support Services
Business/Commerce, General
Chemistry, General
Education
English Language and Literature, General
English Language and Literature/letters
English/Language Arts Teacher Education
Foreign Languages, Literatures, and Linguistics
History
History, General
Humanities/Humanistic Studies
Liberal Arts and Sciences, General Studies and Humanities
Mathematics and Statistics
Mathematics Teacher Education
Mathematics, General
Multi-/interdisciplinary Studies, General
Natural Sciences
Physical Education Teaching and Coaching
Physical Sciences
Psychology
Psychology, General
Psychology, Other
Science Teacher Education/General Science Teacher Education
Social Sciences
Social Sciences, General
Sociology
Spanish Language and Literature
Spanish Language Teacher Education
Special Education and Teaching, General